TRIMETHYLSILYL CYANIDE, [14C] - Names and Identifiers
TRIMETHYLSILYL CYANIDE, [14C] - Physico-chemical Properties
Molecular Formula | C4H9NSi
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Molar Mass | 101.22 |
TRIMETHYLSILYL CYANIDE, [14C] - Introduction
TRIMETHYLSILYL CYANIDE, [14C] is an organic compound with the chemical formula (CH3)3SiCN, containing the radioactive carbon isotope 14C. It is a colorless liquid and has a special smell at room temperature. The following is a description of the nature, use, preparation and safety information of TRIMETHYLSILYL CYANIDE, [14C]:
Nature:
1. Appearance: colorless liquid.
2. Melting Point:-75 ℃.
3. Boiling point: 101-102 ℃.
4. Density: 0.791 g/mL.
5. Solubility: Soluble in organic solvents, such as ether, tetrahydrofuran and dichloromethane.
Use:
1. TRIMETHYLSILYL CYANIDE, [14C] is commonly used in isotope labeling compounds, such as drugs, ligands and organic reagents, for radioactive tracing and drug metabolism research.
2. It can also be used as a reagent in organic synthesis, commonly used in the construction of carbon-cyano bond.
Preparation Method:
TRIMETHYLSILYL CYANIDE, [14C] is usually prepared by the following steps:
1. Sodium cyanide (Na14CN) containing radioactive carbon isotope 14C is reacted with trimethylchlorosilane in mannitol at room temperature.
2. After the reaction is completed, TRIMETHYLSILYL CYANIDE, [14C] is obtained by distillation and purification.
Safety Information:
1. TRIMETHYLSILYL CYANIDE, [14C] is an organic compound with certain toxicity. Please wear appropriate personal protective equipment, such as gloves, safety glasses and laboratory coats.
2. In use should be careful to avoid contact with skin, eyes and respiratory tract.
3. In case of contact, rinse the affected area immediately with plenty of water and seek medical assistance.
4. Please properly dispose of the compound and its waste, and follow the relevant safety procedures and removal procedures.
Last Update:2024-04-09 02:00:38